EvoMining is an evolution-inspired NP genome mining strategy helpful in the identification of putative novel classes of molecules and biosynthetic systems. EvoMining is based on the identification of expansions on central metabolic enzyme families and their recruitment by NP biosynthetic pathways.
EvoMining predicts novel biosynthetic pathways on microbial genomes using phylogenetic profiles and distances, gene context and tree topology of the expanded enzyme families with recruitments.